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OnlineKidneyDr. Joan J. Morales Lappot, MD · Nephrology
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Creatine supplements and your kidneys: myth versus fact

Dr. Joan J. Morales Lappot, MD
3 min read · Leer en español

In briefCreatine is one of the most popular supplements at the gym, and one of the most common reasons a young, healthy person gets a worrying lab result.

Does creatine hurt healthy kidneys?

In healthy people, studies of creatine at usual doses (about 3 to 5 grams a day) have not shown kidney damage. It is one of the better-studied supplements. That is not true of many "stacks" and pre-workout blends, which can contain stimulants or ingredients with little testing.

Why your creatinine may look high

Creatinine, the lab test we use to estimate kidney function, is made from creatine. Taking creatine and having more muscle both raise creatinine, which makes your eGFR look lower than it truly is. Before calling that kidney disease, I may check cystatin C, a blood test that is not affected by muscle or creatine, or repeat labs after stopping the supplement for a few weeks.

Who should avoid it

  • People with chronic kidney disease
  • People with a single kidney or a kidney transplant, unless their doctor approves
  • Anyone also using high-dose protein, anti-inflammatory pain relievers or other supplements without medical advice
Bottom line: Tell your doctor if you take creatine before your blood work. It can save you from a false alarm, or from missing a real one.
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